Delivery and long-term expression of CCR5-blocking monoclonal antibody Leronlimab with AAV for ART-free remission from SHIV viremia

AUTHORS

G. Webb^1,2, H. Wu^1,2, C. Waytashek^1,2, C. Boyle^1,2, J. Hwang^1,2, H. Fisher^1,2, C. Pessoa^1,2, M. Humkey^1,2, A. McCullen^1,2, M. Brown^1,2, K. Kukula^1,2, J. Smedley¹, J. Zikos³, D. Magnani³, S. Fuchs⁴, R. Desrosiers⁴, J. Sacha^1,2


INSTITUTIONS

¹Oregon Health and Science University, Oregon National Primate Research Center, Beaverton, United States, ²Oregon Health and Science University, Vaccine and Gene Therapy Institute, Beaverton, United States, ³University of Massachusetts Medical School, MassBiologics, Boston, United States, ⁴University of Miami, Miller School of Medicine, Miami, United States