The 11th symposium on children and adolescents with perinatal HIV exposure: Session 3 - Evidence to inform action

This symposium builds on a decade of meetings focused on the health and well-being of infants, children and adolescents born HIV free to women living with HIV, a population that is estimated to exceed 16 million globally. Perinatal HIV and antiretroviral drug exposure makes these children more vulnerable than others to infectious morbidity, mortality, impaired growth and suboptimal neurodevelopmental and cognitive outcomes – despite starting life HIV free.

As our understanding evolves, a multifaceted approach is needed to understand the impact of newer HIV treatment options available for pregnant persons with HIV, identify those at risk for poorer outcomes, and continue research on the mechanistic pathways of observed differences, the screening tools, interventions, policy development, and advocacy needed to optimize the health of children and adolescent born HIV-free to women living with HIV.

This symposium, “Taking action to ensure that children and adolescents with perinatal exposure thrive,” present the latest scientific findings and address health policy and programming to support children with perinatal exposure to thrive. It fosters networking opportunities for researchers, policy makers, implementers, community members and advocates.

13 July 2025
English
Chairs
Priscilla Ruvimbo Tsondai

Priscilla Ruvimbo Tsondai

International AIDS Society

Jessica Jexler

Jessica Jexler

NGO

Speakers
Victoria Chuwa

Victoria Chuwa

UNICEF

Session outline

Gosego Masasa

Botswana Harvard Health Partnership

Oral Abstract 1 - Gestational exposure to an efavirenz-containing compared to a dolutegravir-containing antiretroviral regimen is associated with lower anthropometrics at 18 months of life among children HIV-exposed uninfected in Botswana

Christabell Mdhluli

Blantyre Malaria Project

Oral Abstract 2 - The Association Between Low Birth Weight and Neurocognitive Development and the impact of Exposure to HIV in Utero
Laurie Gulaid

Laurie Gulaid

UNICEF

Jane Namangolwa Mutanga

Jane Namangolwa Mutanga

Independent consultant

Priscilla Ruvimbo Tsondai

Priscilla Ruvimbo Tsondai

International AIDS Society

Debate – Children and adolescents with perinatal HIV exposure require long-term follow-up and dedicated funding and support

Sonia Lee

NIH

Closing remarks