Planet of the Apes: Learning immunogenicity from animal models
Chairs
Michaela Muller-Trutwin
Institut Pasteur
Christina Karsten
Institute for The Research on HIV and AIDS-associated Diseases, University Duisburg-Essen
Speakers
Michaela Muller-Trutwin
Institut Pasteur
Christina Karsten
Institute for The Research on HIV and AIDS-associated Diseases, University Duisburg-Essen
Introduction
Jonah Sacha
Oregon Health & Science University
Short-term combination immunotherapy with broadly neutralizing antibodies and CCR5 blockade mediates ART-free viral control in infant rhesus macaques
- presentation-slides.pptx (35.84 MB)
Ashley Nelson
Weill Cornell Medicine
Induction of precursor CD4 binding-site targeting broadly neutralizing antibodies in infant macaques following immunization with germline-targeting SOSIP trimers
- presentation-slides.pptx (9.15 MB)
Dominique Davis
The University of North Carolina at Chapel Hill
Induction of V3 glycan-directed responses post CH848 gp160 mRNA-LNP vaccination in infant rhesus macaques
- presentation-slides.pptx (11.47 MB)
Yasmine Issah
Weill Cornell Medicine
Immunogenicity of HIV BG505 germline-targeting GT1.1 SOSIP envelope trimer immunization in infant and juvenile rhesus macaques
- presentation-slides.pptx (10.26 MB)
Ann Chahroudi
Emory School of Medicine
Anti-SIV Env RhmAbs +/- CD8a depletion and N-803 in ART-suppressed rhesus macaques leads to post-treatment control of viremia associated with transcriptomic changes in CD8+ and CD4+ T cells
- presentation-slides.pptx (17.84 MB)
Maria P Lemos
Fred Hutchinson Cancer Center
Intravenously delivered broadly neutralizing antibody VRC01 reaches the rectal lamina propria and provides partial protection in ex-vivo challenges with HIV-1 (HVTN116)
- presentation-slides.pptx (181.52 MB)
Michaela Muller-Trutwin
Institut Pasteur
Christina Karsten
Institute for The Research on HIV and AIDS-associated Diseases, University Duisburg-Essen
Jonah Sacha
Oregon Health & Science University
Ashley Nelson
Weill Cornell Medicine
Dominique Davis
The University of North Carolina at Chapel Hill
Yasmine Issah
Weill Cornell Medicine
Ann Chahroudi
Emory School of Medicine
Maria P Lemos
Fred Hutchinson Cancer Center
Q&A and conclusion